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Other drugs may interact with acetaminophen , including prescription and over-the-counter medicines, vitamins, and herbal products --- drugs com acetaminophen htmlIs acetaminophen a prescription drug? Generic Name Acetaminophen DrugBank Accession Number DB00316 Background Acetaminophen (paracetamol), also commonly known as Tylenol , is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO) 10 It is also used for its antipyretic effects, helping to reduce fever 23 This drug was initially approved by the Stop taking Tylenol and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling What other drugs will affect Tylenol? 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